The incident took place at about 3pm along Tumpuna Road, Arima.
Police were told the victims were driving to another destination having just left the bank when they made a stop in the vicinity of T&TEC.
At that point, a silver Toyota Axio motor vehicle pulled alongside them.
Two men exited, armed with firearms and announced a holdup.
They then relieved the victims if their funds, before returning to the vehicle and driving away.
The police were notified, and investigations into this incident are ongoing.